HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trolox → HCID 67263003, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trolox | HCID 40634 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Product | HCID 67263003 | HCID 67263003 | 83.4% |
Reaction Steps
Following the amide coupling procedure described in protocol A, 502 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2.01 mmol), 354 mg CDI (2.18 mmol) and 220 mg N-methylpiprazine (2.2 mmol) produced 557 mg of (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(4-methylpiperazin-1-yl)methanone as a clear oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519001B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-891c57be6e964d7e98ddd049b20293af |
| Source note | uspto-grants-2013_08 |