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HRID1898716

反应详情

EQUATION

反应方程式

HRID 1898716 的结构方程式

REACTANTS

反应物

3
结构：NCc1ccccn1
HCID19509

2-Pyridinemethanamine

C6H8N2

结构：Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2
HCID40634

Trolox

C14H18O4

结构：O=C(n1ccnc1)n1ccnc1
HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

PRODUCTS

生成物

1
结构：Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCc1ccccn1)O2
HCID21737544

未命名化合物

收率 85.5%

PROCEDURE

实验过程

Following the amide coupling procedure described in protocol A, 499 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (1.99 mmol), 370 mg CDI (2.28 mmol) and 324 mg 2-picolylamine (3.0 mmol), produced 579 mg of 6-hydroxy-2,5,7,8-tetramethyl-N-(pyridin-2-ylmethyl)chroman-2-carboxamide as a white solid.