HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-Acetoxy-2-formyl-4-methoxycinnamate → Methyl 5-Acetoxy-2-formyl-4-methoxyhydrocinnamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-Acetoxy-2-formyl-4-methoxycinnamate | HCID 53756943 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 5-Acetoxy-2-formyl-4-methoxyhydrocinnamate | HCID 23372351 | — |
Reaction Steps
A mixture of methyl 5-acetoxy-2-formyl-4-methoxycinnamate (10.8 g) and 10% palladium on carbon (3 g) in ethyl acetate (100 ml) is hydrogenated at 45 psi for about 18 hours and filtered. The filtrate is concentrated in vacuo and the residue purified by HPLC, eluting 50% ethyl acetate in hexanes, to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05571506 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-d02b5e2cb1c64e93bd705cc8158c50d1 |
| Source note | uspto-grants-1996_11 |