反应详情

A mixture of methyl 5-acetoxy-2-formyl-4-methoxycinnamate (10.8 g) and 10% palladium on carbon (3 g) in ethyl acetate (100 ml) is hydrogenated at 45 psi for about 18 hours and filtered. The filtrate is concentrated in vacuo and the residue purified by HPLC, eluting 50% ethyl acetate in hexanes, to give the desired product.

1. filtrationfiltered
2. concentrationThe filtrate is concentrated in vacuo
3. customthe residue purified by HPLC
4. washeluting 50% ethyl acetate in hexanes