HCID 178449491, compound → HCID 54432118, compound

Participants

Reaction Steps

As in Example 51, 1.80 g (4.26 mmol) of 1-cyano-1-[N-butyl-N-(3-trifluoromethylphenyl)carbamoyl]-2-[imino(2-oxo-1-imidazolidinyl)methylamino]ethene (compound II, R1, R2, R3, R5, R6 =H; R4 =n-C4H9) and 4.7 ml of glacial acetic acid were stirred at 60° for 4 hours and subsequently worked up. 0.85 g (=47.3% yield) of pure 4-amino-2-(2-oxo-1-imidazolidinyl)pyrimidine-5-carboxylic acid N-butyl-N-(3-trifluoromethylphenyl)amide was obtained, melting point 234°-235°.

Provenance & Evidence