Hydrochloric Acid → HCID 67769409, compound

HRID 1898919Notes

Reaction equation

HRID 1898919 reaction equation
C1([CH2:4][N:5]([C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[CH:26]=[CH:25][C:24]=2F)[C:6]([C:8]2[C:9]([NH2:22])=[N:10][C:11]([N:14]3[CH2:18][C:17](C)(C)[NH:16][C:15]3=[O:21])=[N:12][CH:13]=2)=[O:7])CC1.[ClH:34]>>[ClH:34].[CH3:4][N:5]([C:23]1[CH:24]=[CH:25][CH:26]=[C:27]([C:29]([F:31])([F:30])[F:32])[CH:28]=1)[C:6]([C:8]1[C:9]([NH2:22])=[N:10][C:11]([N:14]2[CH2:18][CH2:17][NH:16][C:15]2=[O:21])=[N:12][CH:13]=1)=[O:7]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 9869137HCID 9869137, compound

Product 1

HCID 67769409HCID 67769409, compound

Procedure

2.853 g (7.5 mmol) of the compound I prepared as in Examples 62 and 63 were converted into the hydrochloride as in Example 6. 3.12 g of 4-amino-2-(2-oxo-1-imidazolidinyl)pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethylphenyl)amide hydrochloride were obtained, melting point 201°-202°.

Sources & evidence

ORD record
ord-281a127845ec4c61a17a41fbbc78ba84
Source dataset
uspto-grants-1996_11
Patent number
US05571816

Reaction notes

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