Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-(Propan-2-yl)benzene-1-sulfonyl fluoride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium Fluoride | HCID 522689 | — |
| 반응물 | 2-(Propan-2-yl)benzene-1-sulfonyl chloride | HCID 12916482 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-(Propan-2-yl)benzene-1-sulfonyl fluoride | HCID 23373130 | 96.1% |
반응 단계
27 g of 2-isopropylbenzenesulfonyl chloride and 22 g of KF are stirred in 75 ml of dioxane and 20 ml of water at 45° C. for 27 h and at RT for 45 h. 800 ml of water are then added, and the mixture is extracted with 3×300 ml of EA. The combined organic phases are dried over Na2SO4 and the solvent is removed in vacuo. 24 g of a colorless oil are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05571842 |
| 출처 데이터셋 | uspto-grants-1996_11 |
| ORD ID | ord-f3291efbbab14b2a9a7fef2bd49b44d7 |
| 출처 메모 | uspto-grants-1996_11 |