Hydroxyamine hydrochloride → 1-Oximino-2-(4-phenylsemicarbazono)-3-indanone

HRID 1899053Notes

Reaction equation

HRID 1899053 reaction equation
Cl.[NH2:2][OH:3].C([O-])(=O)C.[Na+].[C:9]1([NH:15][C:16](=[O:30])[NH:17][N:18]=[C:19]2[C:27](=[O:28])[C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[C:20]2=O)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>O.C(O)C>[N:2](=[C:20]1[C:21]2[C:26](=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:27](=[O:28])[C:19]1=[N:18][NH:17][C:16]([NH:15][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:30])[OH:3]

Participants

6

Reactant 3

HCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium AcetateHCID 101084352-(4-Phenyl semicarbazono)-indan-1,3-dione

Product 1

HCID 1363335631-Oximino-2-(4-phenylsemicarbazono)-3-indanone

Reagents, catalysts & solvents 2

HCID 702EthanolSolvent2×HCID 962WaterSolvent

Procedure

0.01 mol of hydroxylamine hydrochloride and 0.01 mol sodium acetate in solution in 20 ml water were added to a solution of 0.01 mol of 2-(4-phenyl semicarbazono)-indan-1,3-dione in 150 ml ethanol. The reaction mixture was refluxed for 1 hour, then the ethanol was eliminated at reduced pressure. The resulting crystals were dried on suction pump, washed in water, dried and recrystallised from isopropanol.

Workup

  1. temperatureThe reaction mixture was refluxed for 1 hour
  2. customThe resulting crystals were dried on suction pump
  3. washwashed in water
  4. customdried
  5. customrecrystallised from isopropanol

Sources & evidence

ORD record
ord-88092d8900e44ae1a04e9fa8f59ae486
Source dataset
uspto-grants-1996_11
Patent number
US05571843

Reaction notes

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