Phosphorus pentachloride → HCID 53856516, compound

HRID 1899067Notes

Reaction equation

HRID 1899067 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:9](=[CH:13][C:14]2[CH:19]=[CH:18][C:17]([S:20][CH3:21])=[CH:16][CH:15]=2)[C:10](O)=[O:11])[CH:5]=[CH:6][C:7]=1[F:8].P(Cl)(Cl)(Cl)(Cl)[Cl:23]>ClCCl>[F:1][C:2]1[CH:3]=[C:4]([C:9](=[CH:13][C:14]2[CH:19]=[CH:18][C:17]([S:20][CH3:21])=[CH:16][CH:15]=2)[C:10]([Cl:23])=[O:11])[CH:5]=[CH:6][C:7]=1[F:8]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 53894677HCID 53894677, compound

Product 1

HCID 53856516HCID 53856516, compoundYield 102.2%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of 2-(3,4-difluorophenyl)-3-[4-(methylthio)phenyl]acrylic acid (12 g) and phosphorus pentachloride (9.0 g) in dichloromethane (120 ml) was stirred for 1 hour. The solvent was evaporated to give a solid of 2-(3,4-difluorophenyl)-3-[4-(methylthio)phenyl]acryloyl chloride (13 g).

Workup

  1. customThe solvent was evaporated

Sources & evidence

ORD record
ord-8c811f620af845b1a74e4e191b94c9eb
Source dataset
uspto-grants-1996_11
Patent number
US05571810

Reaction notes

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