Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 23372733 | HCID 23372733 | — |
| Product | HCID 23372700 | HCID 23372700 | — |
Reaction Steps
A mixture of ethyl 5-[4-(N-formylmethylamino)phenyl]-4-[4-(methylsulfonyl)phenyl]thiophene-2-carboxylate (0.34 g) and sodium methoxide (0.13 g) in formamide (2 ml) was stirred at 100° C. for 2.5 hours. The mixture was poured into ice-water and the precipitates were collected to give 5-[4-(N-formylmethylamino)phenyl]-4-[4-(methylsulfonyl)phenyl]thiophene-3-carboxamide (0.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05571810 |
|---|
| Source dataset | uspto-grants-1996_11 |
|---|
| ORD ID | ord-2a20d1ac90f94f828498d9381d71879d |
|---|
| Source note | uspto-grants-1996_11 |
|---|
