HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Chloronicotinoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Chloronicotinic acid | HCID 76258 | — |
| Product | 2-Chloronicotinoyl chloride | HCID 2774541 | — |
Reaction Steps
2-chloronicotinic acid chloride was prepared by refluxing 90g (0.571 mole) of 2-chloronicotinic acid in 315ml of thionylchloride for 2 hours. The excess thionylchloride was distilled off. The residue was diluted with 200ml of 1,4-dioxane and used as is.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05571912 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-ca83247249cd4fd88a3a8bae7589e6f6 |
| Source note | uspto-grants-1996_11 |