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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1899399Generated: November 2, 2026

Chloromethyl Methyl Ether → 1H-Pyrrole-3-carboxylic acid, 5-formyl-1-(methoxymethyl)-, methyl ester

https://huagongshe.com/reaction/1899399

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloromethyl Methyl EtherHCID 7864—
ReactantMethyl 5-formylpyrrole-3-carboxylateHCID 579027—
Product1H-Pyrrole-3-carboxylic acid, 5-formyl-1-(methoxymethyl)-, methyl esterHCID 602853—

Reaction Steps

reacting a methyl 2-formyl-4-pyrrolcarboxylate with chloromethyl-methyl-ether in the presence of a base and a suitable organic solvent, obtaining as a reaction product methyl 2-formyl-N-methoxymethyl-4-pyrrolcarboxylate;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05571927
Source datasetuspto-grants-1996_11
ORD IDord-8bb95edff52a4e959f8c81fdbc5575cb
Source noteuspto-grants-1996_11