HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Naphthalenesulfonyl chloride → N-(4-Methyl-3-trifluoromethyl-5-isoxazolyl)-1-naphthalenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Naphthalenesulfonyl chloride | HCID 66560 | — |
| Reactant | 4-Methyl-3-(trifluoromethyl)isoxazol-5-amine | HCID 15613878 | — |
| Product | N-(4-Methyl-3-trifluoromethyl-5-isoxazolyl)-1-naphthalenesulfonamide | HCID 23372919 | 85% |
Reaction Steps
N-(4-Methyl-3-trifluoromethyl-5-isoxazolyl)-1-naphthalenesulfonamide was prepared, as described in Example 90, from 5-amino-4-methyl-3-trifluoromethylisoxazole and 1-naphthalenesulfonyl chloride in 85% yield. Purification was achieved by recrystallization from methanol/water to give white needed, m.p. 154°-155° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05571821 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-5730c4a9f959427db5f063a3d44243eb |
| Source note | uspto-grants-1996_11 |