Pyrrole → N-(5-bromothiophenesulfonyl)pyrrole

HRID 1899725Notes

Reaction equation

HRID 1899725 reaction equation
[Br:1][C:2]1[S:6][C:5]([S:7](Cl)(=[O:9])=[O:8])=[CH:4][CH:3]=1.[NH:11]1[CH:15]=[CH:14][CH:13]=[CH:12]1>>[Br:1][C:2]1[S:6][C:5]([S:7]([N:11]2[CH:15]=[CH:14][CH:13]=[CH:12]2)(=[O:9])=[O:8])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 8027PyrroleHCID 27339245-Bromothiophene-2-sulfonyl chloride

Product 1

HCID 23445587N-(5-bromothiophenesulfonyl)pyrroleYield 88%

Procedure

N-(5-Bromothiophene-2-sulfonyl)pyrrole was prepared in the same manner as described in Example 33A from 5-Bromothiophene-2-sulfonyl chloride and pyrrole in 88% yield. This was purified by recrystallization using hexane/ethyl acetate as a solvent.

Workup

  1. customThis was purified by recrystallization

Sources & evidence

ORD record
ord-b910cc93f8ee4972ad4fe84cc83203f5
Source dataset
uspto-grants-1996_11
Patent number
US05571821

Reaction notes

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