3-Bromoanisole → 3-Methoxyphenylboric acid

HRID 1899726Notes

Reaction equation

Br[C:2]1[CH:3]=[C:4]([O:8][CH3:9])[CH:5]=[CH:6][CH:7]=1.[B:10]([O:19]C(C)C)([O:15]C(C)C)[O:11]C(C)C>>[CH3:9][O:8][C:4]1[CH:3]=[C:2]([O:11][B:10]([OH:19])[OH:15])[CH:7]=[CH:6][CH:5]=1

Participants

Reactant 2

HCID 169713-Bromoanisole

HCID 21531Triisopropyl borate

Product 1

HCID 221738233-Methoxyphenylboric acidYield 82%

Procedure

3-Methoxyphenylboric acid was prepared in the same manner as described in Example 33B from 3-bromoanisole and triisopropyl borate in 82% yield. This was used in the next step without any further purification.

Workup

customThis was used in the next step without any further purification

Sources & evidence

ORD record: ord-19aa0f67b36043399b1a8aec15694ffa
Source dataset: uspto-grants-1996_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05571821

Reaction notes

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