4-Bromoanisole → 4-Methoxyphenyl boric acid

HRID 1899729Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][CH:3]=1.[B:10]([O:19]C(C)C)([O:15]C(C)C)[O:11]C(C)C>>[CH3:9][O:8][C:5]1[CH:6]=[CH:7][C:2]([O:11][B:10]([OH:19])[OH:15])=[CH:3][CH:4]=1

Participants

Reactant 2

HCID 77304-Bromoanisole

HCID 21531Triisopropyl borate

Product 1

HCID 147699944-Methoxyphenyl boric acidYield 69%

Procedure

4-Methoxyphenylboric acid was prepared in the same manner as described in Example 33B from 4-bromoanisole and triisopropyl borate in 69% yield. This was used in the next step without any further purification.

Workup

customThis was used in the next step without any further purification

Sources & evidence

ORD record: ord-dcb77c4715cc4993aa4018e3fb4442ae
Source dataset: uspto-grants-1996_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05571821

Reaction notes

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