反应详情

温度

25 °C

Methacryloyl chloride (8.0 g, 0.078 mmol) in methylene chloride (10 ml) was added to a solution of 1,3-diaminopropane (35 ml) in methylene chloride (200 ml) at 0° C. After 15 min. stirring at 0° C. and 16 hours at 25° C. the reaction mixture was filtered and concentrated under reduced pressure. The residue was purified by flash chromatography (silicagel, chloroform/methanol (8:2)) to give (72%) of the title compound.

1. filtrationwas filtered
2. concentrationconcentrated under reduced pressure
3. customThe residue was purified by flash chromatography (silicagel, chloroform/methanol (8:2))