HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-(2-Nitrophenyl)-4-(3-trifluoromethylphenyl)-1-piperazinpropionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-(3-(Trifluoromethyl)phenyl)piperazine | HCID 4296 | — |
| Reactant | 3-bromo-N-(2-nitrophenyl)propionamide | HCID 14762583 | — |
| Product | N-(2-Nitrophenyl)-4-(3-trifluoromethylphenyl)-1-piperazinpropionamide | HCID 33473794 | — |
Reaction Steps
The compound was prepared from 3-bromo-N-(2-nitrophenyl)propionamide and 1-(3-trifluoromethylphenyl)piperazine according to the method described in J. Med. Chem. 33, 2970 (1990). Monohydrochloride salt. M.p. 185°-188° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05576318 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-16ee469600994a3cb1576b6769680d05 |
| Source note | uspto-grants-1996_11 |