Hydrazine hydrate (1:1) → HCID 14976001, compound

HRID 1900600Notes

Reaction equation

HRID 1900600 reaction equation
[F:1][C:2]([F:15])([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)[C:3](OCC)=[O:4].[NH2:16][NH2:17].O>CCO>[F:1][C:2]([F:15])([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)[C:3]([NH:16][NH2:17])=[O:4]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 14975998HCID 14975998, compound

Product 1

HCID 14976001HCID 14976001, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The product of Example 66 (0.18 g, 0.84 mmol) was dissolved in 5 mL of EtOH. To the solution was added NH2NH2.H2O (0.084 g, 1.7 mmol). The reaction was complete in 1 hour. The solvent-was removed under vacuum. The structure was confirmed by 1H NMR.

Workup

  1. customThe solvent-was removed under vacuum

Sources & evidence

ORD record
ord-9a4b361abf6c40bdb9fe4fe5e1b7dbc8
Source dataset
uspto-grants-1996_11
Patent number
US05576315

Reaction notes

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