Hydrochloric Acid → HCID 23369566, compound

Participants

Reaction Steps

A hydrochloric acid salt of 2-aminomethyl-5-methyl-1,2-dihydrofuro-[3,2-f]quinoline-7-one (1.0 g) was dissolved in water (50 ml). To the solution, 10% palladium-on-carbon (1 g) was added, followed by stirring at 80° C. for 1.5 hours in the atmosphere of hydrogen. After the catalyst was removed by filtration, the mixture was condensed. The resultant residue was recrystallized from methanol--ether to obtain 642 mg of a hydrochloric acid salt of 2-aminomethyl-5-methyl-1,2,8,9-tetrahydrofuro-[3,2-f]quinoline-7-one as colorless prisms (63.7%).

Provenance & Evidence