HCID 23369730, compound → HCID 23369779, compound

Participants

Reaction Steps

The compound obtained in Example 257 (3 g, 11 mmol) was dissolved in acetic acid (50 ml). To the solution, 10% palladium-on-carbon (3 g) was added, followed by stirring at 80° C. for 4 hours in the stream of hydrogen to carry out hydrogenation. After completion of the reaction, palladium-on-carbon was removed by filtration. The filtrate was thoroughly washed with chloroform and methanol, and condensed. As a result, 3 g of the title compound was obtained as a white solid (99%).

Provenance & Evidence