HCID 23369825, compound → HCID 23369637, compound

HRID 1900796Notes

Reaction equation

HRID 1900796 reaction equation
[N:1]([CH2:4][CH:5]1[O:21][C:8]2=[C:9]3[C:14](=[C:15]([CH3:17])[CH:16]=[C:7]2[CH2:6]1)[NH:13][C:12](=[O:18])[CH2:11][C:10]3([CH3:20])[CH3:19])=[N+]=[N-].[H][H]>CN(C)C=O.[Pd]>[NH2:1][CH2:4][CH:5]1[O:21][C:8]2=[C:9]3[C:14](=[C:15]([CH3:17])[CH:16]=[C:7]2[CH2:6]1)[NH:13][C:12](=[O:18])[CH2:11][C:10]3([CH3:19])[CH3:20]

Participants

5

Reactant 2

HCID 23369825HCID 23369825, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 23369637HCID 23369637, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 6228DimethylformamideSolvent

Procedure

The compound obtained in Example 265 (2.69 g, 9.41 mmol) was dissolved in N,N-dimethylformamide (40 ml). To the resultant solution, 10% palladium-on-carbon (1.2 g) was added, followed by stirring at room temperature for 3 hours in the atmosphere of hydrogen.

Sources & evidence

ORD record
ord-ab1287b6c66141199b2e17028049e2ba
Source dataset
uspto-grants-1996_11
Patent number
US05576324

Reaction notes

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