Sodium Azide → HCID 23369774, compound

HRID 1900833Notes

Reaction equation

Br[CH2:2][CH:3]1[O:19][C:6]2=[C:7]3[C:12](=[C:13]([CH3:15])[CH:14]=[C:5]2[CH2:4]1)[NH:11][C:10](=[O:16])[C:9]([CH3:18])([CH3:17])[CH2:8]3.[N-:20]=[N+:21]=[N-:22].[Na+]>>[N:20]([CH2:2][CH:3]1[O:19][C:6]2=[C:7]3[C:12](=[C:13]([CH3:15])[CH:14]=[C:5]2[CH2:4]1)[NH:11][C:10](=[O:16])[C:9]([CH3:18])([CH3:17])[CH2:8]3)=[N+:21]=[N-:22]

Participants

Reactant 2

HCID 33557Sodium Azide

HCID 23369804HCID 23369804, compound

Product 1

HCID 23369774HCID 23369774, compoundYield 86.1%

Procedure

Using the compound obtained in Example 299 (1.93 g 5.96 mmol) and sodium azide (2.8 g, 43.1 mmol), the procedure of Example 278 was followed (reaction, post-treatment, and recrystallization from chloroform-ether). 1.47 g of the title compound was obtained as colorless crystals (86.2%).

Sources & evidence

ORD record: ord-b5c13d7af6fe4201ac399e1830df0a3c
Source dataset: uspto-grants-1996_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05576324

Reaction notes

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