Acetic Acid → HCID 23369836, compound

Participants

Reaction Conditions

Reaction Steps

2-Chloro-3-isopropyl-5-methoxy-8-methylquinoline (2.65 g, 10.6 mmol) was dissolved in acetic acid (70 ml), and the solution was stirred at 120° C. for 15 hours. The reaction solution was condensed under reduced pressure, and the resultant residue was recrystallized from chloroform-ethyl acetate. 2.10 g of the title compound was obtained as pale yellow powdery crystals (85.6%).

Provenance & Evidence