反应详情

To a suspension of 1-(4-methoxy-2-nitrophenyl)-3-cyclopentylurea (0.96 g) in ethanol (15 ml) was added a catalytic amount of 10% palladium/carbon to carry out catalytic reduction at a pressure of 1-2.5 arms at room temperature for 2 hrs. The catalyst was filtered off, the solvent was distilled off and crystallization of the residue from benzene and hexane afforded 1-(2-amino-4-methoxyphenyl)-3-cyclopentylurea (0.79 g, 93%).

1. customat room temperature
2. customfor 2 hrs
3. filtrationThe catalyst was filtered off
4. distillationthe solvent was distilled off
5. customcrystallization of the residue from benzene and hexane