Hydrochloric Acid → N-methyl-4-[[2-(piperidin-3-ylamino)-1,3-benzothiazol-6-yl]oxy]pyridine-2-carboxamide

HRID 190118Notes

Reaction equation

HRID 190118 reaction equation
[CH3:1][NH:2][C:3](=[O:4])[c:5]1[n:6][cH:7][cH:8][c:9]([O:11][c:12]2[cH:13][c:14]3[c:15]([n:16][c:17]([NH:19][CH:20]4[CH2:21][N:22]([C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH2:23][CH2:24][CH2:25]4)[s:18]3)[cH:33][cH:34]2)[cH:10]1.[ClH:41].[O:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1>>[CH3:1][NH:2][C:3](=[O:4])[c:5]1[n:6][cH:7][cH:8][c:9]([O:11][c:12]2[cH:13][c:14]3[c:15]([n:16][c:17]([NH:19][CH:20]4[CH2:21][NH:22][CH2:23][CH2:24][CH2:25]4)[s:18]3)[cH:33][cH:34]2)[cH:10]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 87421339Tert-butyl 3-[[6-[[2-(methylcarbamoyl)-4-pyridinyl]oxy]-1,3-benzothiazol-2-yl]amino]piperidine-1-carboxylate

Product 1

HCID 87421364N-methyl-4-[[2-(piperidin-3-ylamino)-1,3-benzothiazol-6-yl]oxy]pyridine-2-carboxamide

Sources & evidence

ORD record
ord-60f788e8c3ac430fae1a634d8ab284ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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