HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → Methyl 4-(2-oxopropoxy)cinnamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Bromoacetone | HCID 11715 | — |
| Reactant | Methyl p-coumarate | HCID 92203 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 4-(2-oxopropoxy)cinnamate | HCID 53842536 | — |
Reaction Steps
Following a procedure similar to that described in Preparation 3, but using 16 g of methyl 4-hydroxycinnamate, 14.9 g of bromoacetone, 20 g of potassium carbonate and 150 ml of dimethylformamide, the title compound was obtained as crystals, melting at 117°-118° C. (after recrystallization from ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05576340 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-aa097d1100954820b7012c072269e532 |
| Source note | uspto-grants-1996_11 |