HRID1901318

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11776

Triphenylphosphine

C18H15P

结构：Cc1ccc(S(=O)(=O)OCC2CCc3cc(C#N)ccc3C2)cc1

HCID13488730

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(S(=O)(=O)[O-])cc1.N#Cc1ccc2c(c1)CCC(C[P+](c1ccccc1)(c1ccccc1)c1ccccc1)C2

HCID21844271

未命名化合物

收率 55.1%

PROCEDURE

实验过程

24.00 g of 5,6,7,8-tetrahydro-6-[(p-toluenesulfonyl)oxymethyl]-2-naphthalenecarbonitrile and 18.38 g of triphenylphosphine were mixed, and then heated at a temperature of 130° to 140° C. for 15 hours in a sealed container. The resulting reaction product was crystallized from an acetone/n-hexane mixture to obtain 23.3 g of the title compound in the form of light yellow powder.

WORKUP

后处理

temperatureheated at a temperature of 130° to 140° C. for 15 hours in a sealed container
customThe resulting reaction product
customwas crystallized from an acetone/n-hexane mixture

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-99a92a095d03458caeb64307f7279a02
来源数据集: uspto-grants-1996_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05576343
来源说明: uspto-grants-1996_11

反应 SMILES

[C:1]1([CH3:24])[CH:6]=[CH:5][C:4]([S:7]([O:10][CH2:11][CH:12]2[CH2:21][CH2:20][C:19]3[CH:18]=[C:17]([C:22]#[N:23])[CH:16]=[CH:15][C:14]=3[CH2:13]2)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[C:25]1([P:31]([C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)[C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[C:1]1([CH3:24])[CH:2]=[CH:3][C:4]([S:7]([O-:10])(=[O:8])=[O:9])=[CH:5][CH:6]=1.[C:22]([C:17]1[CH:18]=[C:19]2[C:14](=[CH:15][CH:16]=1)[CH2:13][CH:12]([CH2:11][P+:31]([C:32]1[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=1)([C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)[C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[CH2:21][CH2:20]2)#[N:23]