Dicyclohexylcarbodiimide → S-4-Isothiocyanatophenyl 6-butylsulphanylthionaphth-2-oate

HRID 1901404Notes

Reaction equation

HRID 1901404 reaction equation
[N:1]([C:4]1[CH:9]=[CH:8][C:7]([SH:10])=[CH:6][CH:5]=1)=[C:2]=[S:3].[CH2:11]([S:15][C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][CH:25]=1)[CH:22]=[C:21]([C:26](O)=[O:27])[CH:20]=[CH:19]2)[CH2:12][CH2:13][CH3:14].C1(N=C=NC2CCCCC2)CCCCC1>CN(C)C1C=CN=CC=1>[CH2:11]([S:15][C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][CH:25]=1)[CH:22]=[C:21]([C:26]([S:10][C:7]1[CH:8]=[CH:9][C:4]([N:1]=[C:2]=[S:3])=[CH:5][CH:6]=1)=[O:27])[CH:20]=[CH:19]2)[CH2:12][CH2:13][CH3:14]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 233673846-Butylsulphanylnaphth-2-oic acidHCID 233673904-Isothiocyanatobenzene-1-thiol

Product 1

HCID 15474614S-4-Isothiocyanatophenyl 6-butylsulphanylthionaphth-2-oate

Reagents, catalysts & solvents 1

HCID 142844-(Dimethylamino)pyridineCatalyst

Procedure

Quantities: compound 3 (0.64 g, 2.0 mmol), compound 13 (0.33 g, 1.9 mmol), 4-(dimethylamino)pyridine (0.10 g, 0.80 mmol), N,N'-dicyclohexylcarbodiimide (0.50 g, 2.4 mmol).

Sources & evidence

ORD record
ord-27062812ca864b83b72dc02ccf4c55d0
Source dataset
uspto-grants-1996_11
Patent number
US05578242

Reaction notes

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