Hydrochloric Acid → HCID 70277694, compound

HRID 1901467Notes

Reaction equation

HRID 1901467 reaction equation
[N:1]1([NH:6][C:7]2[C:8]([CH3:19])=[C:9]3[C:14](=[C:15]([CH3:17])[CH:16]=2)[N:13]=[CH:12][CH:11]=[C:10]3[CH3:18])[CH2:5][CH2:4][N:3]=[CH:2]1.CC[O:22]CC.[ClH:25]>CO>[OH2:22].[ClH:25].[ClH:25].[N:1]1([NH:6][C:7]2[C:8]([CH3:19])=[C:9]3[C:14](=[C:15]([CH3:17])[CH:16]=2)[N:13]=[CH:12][CH:11]=[C:10]3[CH3:18])[CH2:5][CH2:4][N:3]=[CH:2]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 67663576HCID 67663576, compound

Product 1

HCID 70277694HCID 70277694, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

6-(2-Imidazolinylamino)-4,5,8-trimethylquinoline (0.406 g) is dissolved in a solution of concentrated hydrochloric acid (0.813 mL) in methanol (4 mL). To this solution is added ether (7 mL). The solution is allowed to stand at room temperature for 3 days, and the resulting crystals are filtered and washed with ether to provide 6-(2-imidazolinylamino)-4,5,8-trimethylquinoline dihydrochloride monohydrate.

Workup

  1. filtrationthe resulting crystals are filtered
  2. washwashed with ether

Sources & evidence

ORD record
ord-87a2e581a18c4690a50517f1afe21d2f
Source dataset
uspto-grants-1996_11
Patent number
US05578607

Reaction notes

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