Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S)- → HCID 86749572, compound

HRID 1901487Notes

Reaction equation

HRID 1901487 reaction equation
[N:1]12[CH2:9][CH:5]([C:6](=[O:8])[CH2:7]1)[CH2:4][CH2:3][CH2:2]2.[C:10]12([CH2:20][S:21]([OH:24])(=[O:23])=[O:22])[C:17]([CH3:19])([CH3:18])[CH:14]([CH2:15][CH2:16]1)[CH2:13][C:11]2=[O:12]>O>[C:10]12([CH2:20][S:21]([OH:24])(=[O:22])=[O:23])[C:17]([CH3:19])([CH3:18])[CH:14]([CH2:15][CH2:16]1)[CH2:13][C:11]2=[O:12].[N:1]12[CH2:9][CH:5]([C:6](=[O:8])[CH2:7]1)[CH2:4][CH2:3][CH2:2]2

Participants

4

Reactant 2

HCID 18462Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S)-HCID 4183471-azabicyclo[3.2.1]octan-6-one

Product 1

HCID 86749572HCID 86749572, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

This compound was made in exactly the same manner as described in example 1 using (±) 1-azabicyclo[3.2.1]octan-6-one and (-) camphorsulfonic acid. M.p. 267°-268° C. (decomp.) [α]D =-48° (water).

Sources & evidence

ORD record
ord-79178b8cb5ec4043979f874c333faaeb
Source dataset
uspto-grants-1996_11
Patent number
US05578602

Reaction notes

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