HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67733471, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | HCID 67733472 | HCID 67733472 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67733471 | HCID 67733471 | — |
Reaction Steps
To a solution of 0.38 g of (R)-3-(2-amino-3-methanesulfonylpropoxy)-5-chloro-1,2-benzoisoxazole in 4 ml of methylene chloride is added 1 ml of a 2-propanol solution (6.5M) of hydrogen chloride, and the crystals precipitated are collected by filtration, to obtain 0.22 g of colorless, crystalline (R)-3-(2-amino-3-methanesulfonylpropoxy)-5-chloro-1,2-benzoisoxazole hydrochloride having a melting point of 189.9°-192.5° C. (decomp.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05578627 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-f4e7cebd8b9041a080b6d0366fd7ebea |
| Source note | uspto-grants-1996_11 |