HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 1-Amino-2-phenylthio-2-propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 3-Phenylthio-2-hydroxypropylazide | HCID 21474763 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Amino-2-phenylthio-2-propanol | HCID 113732 | 97.1% |
Reaction Steps
A procedure similar to that described in Preparation 13 was repeated, except that 8 g of 3-phenylthio-2-hydroxypropylazide (prepared as described in Preparation 86), 2.9 g of lithium aluminum hydride and 400 ml of anhydrous tetrahydrofuran were used, to give 6.8 g of the title compound, melting at 57° C. to 61° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05578620 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-079868872b804ada9b447e99b25724fd |
| Source note | uspto-grants-1996_11 |