Isovaleryl chloride → HCID 9840009, compound

HRID 1901768Notes

Reaction equation

HRID 1901768 reaction equation
[OH:1][CH2:2][CH2:3][C:4]#[C:5][C:6]1[S:10][C:9]([C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:7]=1.[C:16](Cl)(=[O:21])[CH2:17][CH:18]([CH3:20])[CH3:19]>N1C=CC=CC=1>[C:16]([O:1][CH2:2][CH2:3][C:4]#[C:5][C:6]1[S:10][C:9]([C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:7]=1)(=[O:21])[CH2:17][CH:18]([CH3:20])[CH3:19]

Participants

4

Reactant 2

HCID 66054Isovaleryl chlorideHCID 4403573-Butyn-1-ol, 4-(5-(2-thienyl)-2-thienyl)-

Product 1

HCID 9840009HCID 9840009, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

5-(4-Hydroxy-1-butynyl)-2,2'-bithiophene (1 g) was dissolved in pyridine (10 ml). Isovaleroyl chloride (1 ml) was added at room temperature, stirred for few minutes and kept overnight. The reaction mixture was treated as in example 21. Light yellowish oily product (1.06 g) was then obtained.

Workup

  1. additionThe reaction mixture was treated as in example 21

Sources & evidence

ORD record
ord-659f06058caa4604a7250c9d7caa6db9
Source dataset
uspto-grants-1996_11
Patent number
US05578636

Reaction notes

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