Palmitoyl chloride → HCID 18920431, compound

HRID 1901770Notes

Reaction equation

HRID 1901770 reaction equation
[OH:1][CH2:2][CH2:3][C:4]#[C:5][C:6]1[S:10][C:9]([C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:7]=1.[C:16](Cl)(=O)[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31]>N1C=CC=CC=1>[CH2:31]([O:1][CH2:2][CH2:3][C:4]#[C:5][C:6]1[S:10][C:9]([C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:7]=1)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH3:16]

Participants

4

Reactant 2

HCID 8206Palmitoyl chlorideHCID 4403573-Butyn-1-ol, 4-(5-(2-thienyl)-2-thienyl)-

Product 1

HCID 18920431HCID 18920431, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

5-(4-Hydroxy-1-butynyl)-2,2'-bithiophene (0.6 g) was dissolved in pyridine (10 ml). Palmitoyl chloride (1 ml) was added at room temperature, stirred for few minutes and kept overnight. The reaction mixture was treated as in example 21, and 1.2 g of light yellowish crystals were then obtained and the melting point thereof was 68°-69° C.

Workup

  1. additionThe reaction mixture was treated as in example 21, and 1.2 g of light yellowish crystals
  2. customwere then obtained
  3. customthereof was 68°-69° C.

Sources & evidence

ORD record
ord-24ab461d96914bfc861bb6ae812fd90b
Source dataset
uspto-grants-1996_11
Patent number
US05578636

Reaction notes

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