Trifluoroiodomethane → HCID 54017515, compound

HRID 1901960Notes

Reaction equation

HRID 1901960 reaction equation
I[C:2]1[CH:3]=[C:4]([C:8]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19](I)[CH:18]=2)([C:13]([F:16])([F:15])[F:14])[C:9]([F:12])([F:11])[F:10])[CH:5]=[CH:6][CH:7]=1.[F:24][C:25](I)([F:27])[F:26]>[Cu].CN(C)C=O>[F:24][C:25]([F:27])([F:26])[C:2]1[CH:3]=[C:4]([C:8]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([C:9]([F:12])([F:11])[F:10])[CH:18]=2)([C:13]([F:15])([F:14])[F:16])[C:9]([F:10])([F:12])[F:11])[CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 2

HCID 16843TrifluoroiodomethaneHCID 22336523HCID 22336523, compound

Product 1

HCID 54017515HCID 54017515, compound

Reagents, catalysts & solvents 2

HCID 23978CopperCatalystHCID 6228DimethylformamideSolvent

Conditions

Temperature
150 °C

Procedure

A 500 mL autoclave was charged with 44.5 g (80.0 mmol) of 2,2-bis[3-iodophenyl]-1,1,1,3,3,3-hexafluoropropane, 40.09 (204 mmol) of trifluoromethyl iodide, 150 mL of dry N,N-dimethylformamide and copper powder (catalyst), and the mixture was heated at a temperature of 150° C. for 24 hours with stirring. After being cooled, the reaction mixture was filtered to remove the copper powder, and the filtrate was fractionally distillated under a reduced pressure to obtain the aimed compound 2Aa.

Workup

  1. temperatureAfter being cooled
  2. filtrationthe reaction mixture was filtered
  3. customto remove the copper powder

Sources & evidence

ORD record
ord-548744428182433a882af48539b780b0
Source dataset
uspto-grants-1996_11
Patent number
US05578697

Reaction notes

Loading…