Trifluoroacetic acid → HCID 67612562, compound

HRID 1902156Notes

Reaction equation

HRID 1902156 reaction equation
[O:1]=[C:2]1[C:41]2[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=2)[C:4]2([CH2:9][CH2:8][N:7]([C:10]([C@H:12]([NH:22][C:23](=[O:35])[C:24]([NH:27]C(OC(C)(C)C)=O)([CH3:26])[CH3:25])[CH2:13][CH2:14][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[O:11])[CH2:6][CH2:5]2)[CH2:3]1.[F:42][C:43]([F:48])([F:47])[C:44]([OH:46])=[O:45]>ClCCl>[F:42][C:43]([F:48])([F:47])[C:44]([OH:46])=[O:45].[O:1]=[C:2]1[C:41]2[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=2)[C:4]2([CH2:5][CH2:6][N:7]([C:10]([C@H:12]([NH:22][C:23](=[O:35])[C:24]([NH2:27])([CH3:26])[CH3:25])[CH2:13][CH2:14][CH2:15][C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)=[O:11])[CH2:8][CH2:9]2)[CH2:3]1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 67612856HCID 67612856, compound

Product 1

HCID 67612562HCID 67612562, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To the product obtained from Step A in 2 mL of dichloromethane was added 2 mL of trifluoroacetic acid and stirred at RT for 1 h. The reaction mixture was concentrated under reduced pressure to yield the title compound as a colorless solid.

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-0e8b9e63fca64c56bb97ed58acd06306
Source dataset
uspto-grants-1996_11
Patent number
US05578593

Reaction notes

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