Acetone → HCID 12893005, compound

Participants

Reaction Steps

To 50 ml of acetone is added 3.0 g of N-(3-ethoxy-4-chlorophenyl)-3,4,5,6-tetrahydroisophthalimide and a solution of 0.8 g of diethylamine in 5 ml of acetone is dropwise added to the solution over the period of about 3 minutes under stirring at room temperature. The solution is stirred at room temperature for a further 4 hours and the solvent is distilled off under reduced pressure for concentration, and recrystallization of the resultant residue from n-hexane yields 2.2 g of the subject compound.

Provenance & Evidence