Hydrochloric Acid → HCID 54097925, compound

HRID 1902354Notes

Reaction equation

[NH2:1][C:2]1[C:17]([CH2:18][N:19]([CH:22]2[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]2)[CH2:20][CH3:21])=[CH:16][C:5]([C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]Cl)=[O:7])=[CH:4][C:3]=1[Br:28].[Cl:29][C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([Cl:36])[C:31]=1[NH:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=1[CH2:44][C:45]([O-:47])=[O:46].[Na+].Cl>>[NH2:1][C:2]1[C:17]([CH2:18][N:19]([CH:22]2[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]2)[CH2:20][CH3:21])=[CH:16][C:5]([C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][O:47][C:45](=[O:46])[CH2:44][C:39]2[CH:40]=[CH:41][CH:42]=[CH:43][C:38]=2[NH:37][C:31]2[C:30]([Cl:29])=[CH:35][CH:34]=[CH:33][C:32]=2[Cl:36])=[O:7])=[CH:4][C:3]=1[Br:28]

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 5018304Diclofenac sodium

HCID 54480102HCID 54480102, compound

Product 1

HCID 54097925HCID 54097925, compound

Procedure

This compound was prepared from 6-[4-amino-3-bromo-5-(N-ethyl-cyclohexylaminomethyl)-benzamido]-n-hexyl chloride and sodium 2-[(2,6-dichlorophenyl)-amino]-phenylacetate analogous to Example 8. Amorphous hydrochloride.

Sources & evidence

ORD record: ord-f44eff3a55614f7eac9e5cb100b181ed
Source dataset: uspto-grants-1982_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04362738

Reaction notes

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