1-Chloro-2-nitrobenzene → HCID 20515473, compound

Participants

Reaction Steps

38 g of 1-chloro-2-nitrobenzene, 38.8 g of potassium 3-amino-1,4,5-trimethyl-1H-pyrrole-2-carboxylate (crude product from Example 2) and 36 g of ground potassium carbonate (particle size: 0.07 mm) are stirred in 120 ml of 1-methyl-2-pyrrolidone under nitrogen at an internal temperature of 140° C. After 12 hours, a further 3.3 g of 1-chloro-2-nitrobenzene are added. For working up, the mixture is filtered hot, and the residue on the filter is rinsed 3 times with 10 ml of hot (100° C.) 1-methyl-2-pyrrolidone each time. The combined filtrates are further processed without purification.

Provenance & Evidence