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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 190254Generated: October 27, 2026

Tetrahydrofuran → 5-fluoro-2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-N-(2-(vinyloxy)ethoxy)-1,6-dihydropyridine-3-carboxamide

https://huagongshe.com/reaction/190254

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
ReactantO-(2-(Vinyloxy)ethyl)hydroxylamineHCID 21867017—
ReactantMethyl 5-fluoro-2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylateHCID 66673936—
Product5-fluoro-2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-N-(2-(vinyloxy)ethoxy)-1,6-dihydropyridine-3-carboxamideHCID 86612534—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-3ab5f61eea8e4a12bc15e702c440793c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)