Tetrahydrofuran → 5-fluoro-2-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-N-(2-(vinyloxy)ethoxy)-1,6-dihydropyridine-3-carboxamide
Reaction equation
[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:31][Si:32]([N-:33][Si:34]([CH3:35])([CH3:36])[CH3:37])([CH3:38])[CH3:39].[CH:24](=[CH2:25])[O:26][CH2:27][CH2:28][O:29][NH2:30].[F:1][c:2]1[cH:3][c:4]([C:20]([O:22][CH3:21])=[O:23])[c:5]([NH:10][c:11]2[c:12]([F:19])[cH:13][c:14]([S:17][CH3:18])[cH:15][cH:16]2)[n:6]([CH3:9])[c:7]1=[O:8].[Li+:40]>>[F:1][c:2]1[cH:3][c:4]([C:20](=[O:22])[NH:30][O:29][CH2:28][CH2:27][O:26][CH:24]=[CH2:25])[c:5]([NH:10][c:11]2[c:12]([F:19])[cH:13][c:14]([S:17][CH3:18])[cH:15][cH:16]2)[n:6]([CH3:9])[c:7]1=[O:8]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-3ab5f61eea8e4a12bc15e702c440793c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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