Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | t-Butyl bromide | HCID 10485 | — |
| Reactant | Imidazo[2,1-b]benzothiazol-7-amine, 2,3-dihydro- | HCID 12892043 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20514575 | HCID 20514575 | — |
Reaction Steps
A mixture of 3 parts of 2,3-dihydroimidazo[2,1-b]benzothiazol-7-amine, 15 parts of 2-bromo-2-methylpropane and 13.5 parts of N,N-dimethylformamide is stirred for 20 hours at 80° C. The reaction mixture is poured onto 50 parts of water. The precipitated product is filtered off, washed successively with water, 2-propanol and 2,2'-oxybispropane, and dried, yielding 3 parts of N-(2,3-dihydroimidazo[2,1-b]benzothiazol-7-yl)formamide monohydrobromide; mp. 287.3° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04364942 |
|---|
| Source dataset | uspto-grants-1982_12 |
|---|
| ORD ID | ord-ca7c55c5e31c4dbdb335af491f9001e3 |
|---|
| Source note | uspto-grants-1982_12 |
|---|
