反应详情

A stirred mixture of benzyl methyl ketone (26.8 ml) and dimethylformamide dimethyl acetal (30.0 ml) was heated in a distillation apparatus on an oil bath at 95°-100° C. for 11/2 hours. Methanol slowly distilled off. The residual volatiles were removed under vacuum and the resulting oil was crystallised from ether-petroleum spirit (40°-60° C.) to yield the title compound (mp 66° C.).

1. temperaturewas heated in a distillation apparatus on an oil bath at 95°-100° C. for 11/2 hours
2. distillationMethanol slowly distilled off
3. customThe residual volatiles were removed under vacuum
4. customthe resulting oil was crystallised from ether-petroleum spirit (40°-60° C.)