Hydrochloric Acid → 4-Oxo-5-phenyl-4H-pyran-2-carboxylic acid

HRID 1902650Notes

Reaction equation

HRID 1902650 reaction equation
[O:1]=[C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:6][O:5][C:4]([C:14]([O:16]CC)=[O:15])=[CH:3]1.Cl>>[O:1]=[C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:6][O:5][C:4]([C:14]([OH:16])=[O:15])=[CH:3]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 13091198Ethyl 4-oxo-5-phenyl-4H-pyran-2-carboxylate

Product 1

HCID 130911614-Oxo-5-phenyl-4H-pyran-2-carboxylic acid

Procedure

Ethyl 4-oxo-5-phenyl-4H-pyran-2-carboxylate (4.9 g) was heated with concentrated hydrochloric acid (12 ml) on a steam bath for 11/2 hours. The mixture was cooled and the solid title product was recrystallised from ethyl acetate-dimethylformamide (mp 225°-227° C. with decomposition).

Workup

  1. temperatureThe mixture was cooled
  2. customthe solid title product was recrystallised from ethyl acetate-dimethylformamide (mp 225°-227° C. with decomposition)

Sources & evidence

ORD record
ord-36ff2856ffc34546ab9ae5748c545023
Source dataset
uspto-grants-1982_12
Patent number
US04364956

Reaction notes

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