Dimethylformamide dimethyl acetal → HCID 53750645, compound

HRID 1902662Notes

Reaction equation

HRID 1902662 reaction equation
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12](=[O:14])[CH3:13])=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4].CO[CH:17](OC)[N:18]([CH3:20])[CH3:19]>>[CH2:1]([C:5]1[CH:6]=[CH:7][C:8]([C:11](=[CH:17][N:18]([CH3:20])[CH3:19])[C:12](=[O:14])[CH3:13])=[CH:9][CH:10]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 20514643HCID 20514643, compound

Product 1

HCID 53750645HCID 53750645, compound

Procedure

This ketone (4.6 g) was reacted with dimethylformamide dimethyl acetal (4.0 ml) as described in Example 1 to give 3-(4-butylphenyl)-4-dimethylamino-3-buten-2-one which was used without purification to prepare ethyl 5-(4-butylphenyl)-4-oxo-4H-pyran-2-carboxylate (mp 65° C.), by the method described in Example 17.

Sources & evidence

ORD record
ord-ff290418b487459585ebbd29e2b75d58
Source dataset
uspto-grants-1982_12
Patent number
US04364956

Reaction notes

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