HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloro-4-methoxy-2-nitrobenzene → 2,6-Dichloro-3-methoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloro-4-methoxy-2-nitrobenzene | HCID 20513886 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2,6-Dichloro-3-methoxyaniline | HCID 20513888 | — |
Reaction Steps
A solution of 62.4 g of 2,4-dichloro-3-nitroanisole in 750 ml of ethanol is treated with 19 g of Raney-nickel and hydrogenated for 8 hours. The obtained solution is filtered and evaporated in vacuo. The residue is taken up in methylene chloride and the solution is washed with a dilute sodium carbonate solution. After drying the organic phase over sodium sulfate and evaporating in vacuo, there is obtained 2,6-dichloro-3-methoxyaniline of boiling point 84° (0.1 Torr).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04366160 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-1c159d2265fd45d0afddb341e4d04751 |
| Source note | uspto-grants-1982_12 |