Hydrochloric Acid → L-Alanine

HRID 1902879Notes

Reaction equation

HRID 1902879 reaction equation
Cl.[NH2:2][CH:3]([CH3:7])[C:4]([NH2:6])=[O:5].[OH2:8]>>[CH3:7][C@H:3]([NH2:2])[C:4]([OH:8])=[O:5].[CH3:7][C@@H:3]([NH2:2])[C:4]([NH2:6])=[O:5]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 3502872-Aminopropanamide

Product 2

HCID 5950L-AlanineYield 50%HCID 446080(R)-2-aminopropanamideYield 50%

Procedure

The treatment of one solution at 6% of hydrochloride of α-aminopropionamide in water (pH included between 6.5 to 8.5) can be effected by a suspension of cells of strain A4 at 20 to 40 g of dry matter per liter. Quantitatively L-α-alanine (50%) and D-α-aminopropionamide (50%) is obtained. This amide D can either be hydrolized in D-α-alanine by action of strain R 312 (CBS 717.73) or racemized and recycled with a view to the preparation of L-α-alanine.

Sources & evidence

ORD record
ord-80c5a3ce9ca34e96bfc57c1a2ade0858
Source dataset
uspto-grants-1982_12
Patent number
US04366250

Reaction notes

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