2-Mercaptoethanol → HCID 20514205, compound

HRID 1902890Notes

Reaction equation

HRID 1902890 reaction equation
S[CH2:2][CH2:3][OH:4].C([O:9][CH2:10][CH:11]=[CH2:12])C1OC1.[CH:13]1[C:18]([C:19]([O:21]OC(C)(C)C)=O)=[CH:17][CH:16]=[CH:15][CH:14]=1.[CH3:27]N(C)C(=N)N(C)C>>[OH:4][CH2:3][CH2:2][CH2:12][CH2:11][CH:10]([OH:9])[CH2:27][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:18][CH2:19][OH:21]

Participants

5

Reactant 4

HCID 15672-MercaptoethanolHCID 7838Allyl glycidyl ether2×HCID 11966tert-Butyl peroxybenzoateHCID 664601,1,3,3-Tetramethylguanidine

Product 1

HCID 20514205HCID 20514205, compound

Procedure

A 5 liter glass reactor with stirrer, thermometer and reflux condenser was used. 2496 grams (32.0 moles) of 2-mercaptoethanol were taken in this reactor. To this was added dropwise, 1824 grams (16.0 moles) of allyl glycidyl ether with vigorous stirring. The exotherm was controlled by water bath. After addition of allyl glycidyl ether, 3 grams of t-butyl perbenzoate and 0.3 grams of tetramethyl guanidine were added and the solution stirred. The completion of the reaction was determined by IR spectrum. The resulting material, 3,11-dithia, 7-oxa, 1,5,13-trihydroxy tridecane, was obtained in the form of a viscous liquid.

Workup

  1. temperatureA 5 liter glass reactor with stirrer, thermometer and reflux condenser
  2. additionTo this was added dropwise
  3. customThe exotherm was controlled by water bath
  4. additionwere added

Sources & evidence

ORD record
ord-d9550aba19044ff99d78a173a17b7b9c
Source dataset
uspto-grants-1982_12
Patent number
US04366307

Reaction notes

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