Sulfuric Acid → HCID 20467692, compound

HRID 1902999Notes

Reaction equation

HRID 1902999 reaction equation
Cl[C:2]1[S:3][C:4]([S:11]([F:14])(=[O:13])=[O:12])=[CH:5][C:6]=1[S:7]([F:10])(=[O:9])=[O:8].C1N2CN3CN(C2)C[N:16]1C3.S(=O)(=O)(O)O>CO>[NH2:16][C:2]1[S:3][C:4]([S:11]([F:14])(=[O:13])=[O:12])=[CH:5][C:6]=1[S:7]([F:10])(=[O:9])=[O:8]

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 4101HexamethylenetetramineHCID 20467693HCID 20467693, compound

Product 1

HCID 20467692HCID 20467692, compoundYield 79.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
25 °C

Procedure

A mixture of 2-chloro-3,5-bisfluorosulphonylthiophene (8.5 g), hexamine (8.5 g) and methanol (90 ml) was stirred under reflux for one hour. The mixture was cooled to 25° C., poured into dilute sulphuric acid and extracted with ethyl acetate to give the product as an oil (6.3 g).

Workup

  1. temperatureunder reflux for one hour
  2. extractionextracted with ethyl acetate

Sources & evidence

ORD record
ord-36934874ada444b2936876130b56ed7d
Source dataset
uspto-grants-1984_03
Patent number
US04435320

Reaction notes

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